Engineering Biology and Medicine at Small Scales
——From Cell Manipulation, Molecular Screening to Early Cancer Detection
John X.J. Zhang, Ph.D.
Department of Biomedical Engineering, and Microelectronics Research Center，
The University of Texas at Austin
时间： 2013.10.22 11:00——12：00
地点：玉泉校区教三 326
Abstract：Translational biomedical engineering plays an important role in assimilating the advancement of nanomaterials and microdevice engineering towards developing innovative tools for medicine, as well as contributing to the investigations across the multi-scale biological hierarchy with minimal invasions. Our laboratory is currently developing a few novel biotechnologies exploring scale-dependent physical science and the miniaturization technology towards efficient healthcare. In this talk, I will review our research on (1) rapid blood screening devices for circulating tumor cells detection and analysis; (2) quantum dots based near-field imaging microchip for cellular microarray screening and molecular-scale energy transfer process measurements, and (3) MEMS-scanner based endoscopes for in vivo sub-cellular early cancer detection. Nano-Micro scale science, Information, and Biomedicine are integrative components of the research that are used with advanced engineering tools to facilitate biomedical studies and develop point-of-care diagnostics for global health applications.
John X.J. Zhang is an Associate Professor at the University of Texas of Austin (UT Austin) in the Department of Biomedical Engineering, with joint affiliations with Institute for Cellular and Molecular Biology (ICMB), Microelectronics Research Center and Texas Materials Institute. He received his Ph.D. from Stanford University in 2004, and was a Research Scientist at Massachusetts Institute of Technology (MIT), before joining the faculty at UT Austin in 2005.
Zhang’s research focuses on exploring bio-inspired nanomaterials, scale-dependent biophysics, and nanofabrication technology, towards developing new diagnostic devices and methods on probing complex cellular processes and biological networks critical to development and diseases. In particular, his laboratory is leading the development of integrated photonic microsystems (MEMS, micro-electro-mechanical systems), semiconductor chips and nanotechnologies critical to healthcare, defense and environmental applications. He has published over 120 peer reviewed papers and proceedings, presented over 45 invited seminars worldwide, and filed over 15 US patents (3 patents issued).
