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篇名
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Optical virtual imaging at 50 nm lateral resolution with a white-light nanoscope
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期刊
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Nature communications
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DOI
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10.1038/ncomms1211
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作者
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Zengbo Wang1 , Wei Guo1 ,Lin Li et al
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日期
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1 Mar 2011
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摘要
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The imaging resolution of a conventional optical microscope is limited by diffraction to ~ 200 nm in the visible spectrum. Efforts to overcome such limits have stimulated the development of optical nanoscopes using metamaterial superlenses, nanoscale solid immersion lenses and molecular fluorescence microscopy. These techniques either require an illuminating laser beam to resolve to 70 nm in the visible spectrum or have limited imaging resolution above 100 nm for a white-light source. Here we report a new 50-nm-resolution nanoscope that uses optically transparent microspheres (for example, SiO 2, with 2 μ m < diameter < 9 μ m) as far-field superlenses (FSL) to overcome the white-light diffraction limit. The microsphere nanoscope operates in both transmission and reflection modes, and generates magnified virtual images with a magnification up to × 8. It may provide new opportunities to image viruses and biomolecules in real time.
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推荐理由
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1. 这是一篇开创性的著作，是首次成功的实现了“白光照明”“宽场”“远场成像”光学超分辨的实验
2. 这是目前已知的最简单的实现超分辨的方法，介质微球即可，不需要复杂的光路
3. 正因为他的开创性，所以很多机理性的东西还没有搞清楚，留给人们想象的空间很大，换句话说，给后人留下了很多继续研究的潜力
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供稿
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王会会
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